
Sulfasalazine and 5-ASA Medications
OVERVIEW: Helps to reduce the inflammation in the intestinal tract.
WHEN DO WE USE IT: Used to treat Ulcerative Colitis mostly, not commonly used as a primary treatment for Crohn Disease, although maybe used in combination with other therapies.
​
HOW IT'S USED: Doses are often divided into multiple doses each day. The treatment is available in oral and rectal forms.
​
DURATION OF TREATMENT: It can be used to induce and maintain remission, so it can be used for a prolonged period of time.
​
TYPES OF 5-ASA: Sulfasalazine, Asacol, Salofalk, Mesalamine, Pentasa
​
SIDE EFFECTS:
-
Rash (often associated with the sulpha in sulfasalazine)
-
Headaches
-
Increased diarrhea or nausea
-
Sulfasalazine can reduce sperm count, however it does return to normal once dose stopped.
​
​
​